The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice

Genetic crosses are most powerful for linkage analysis when progeny numbers are high, parental alleles segregate evenly and numbers of inbred progeny are minimized. We previously developed a novel genetic crossing platform for the human malaria parasite Plasmodium falciparum, an obligately sexual, h...

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Bibliographic Details
Main Authors: Button-Simons, KA, Kumar, S, Carmago, N, Haile, MT, Jett, C, Checkley, LA, Kennedy, SY, Pinapati, RS, Shoue, DA, McDew-White, M, Li, X, Nosten, FH, Kappe, SH, Anderson, TJC, Romero-Severson, J, Ferdig, MT, Emrich, SJ, Vaughan, AM, Cheeseman, IH
Format: Journal article
Language:English
Published: Springer Nature 2021