Identification of circulating genomic and metabolic biomarkers in intrahepatic cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer arising from the bile ducts with a need for earlier diagnosis and a greater range of treatment options. KRAS/NRAS mutations are common in ICC tumours and 6–32% of patients also have isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) gene mu...

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Bibliographic Details
Main Authors: Winter, H, Kaisaki, PJ, Harvey, J, Giacopuzzi, E, Ferla, MP, Pentony, MM, Knight, SJL, Sharma, RA, Taylor, JC, McCullagh, JSO
Format: Journal article
Language:English
Published: MDPI 2019