The effects of stretch activation on ionic selectivity of the TREK-2 K2P K(+) channel

The TREK-2 (KCNK10) K2P potassium channel can be regulated by variety of polymodal stimuli including pressure. In a recent study, we demonstrated that this mechanosensitive K(+) channel responds to changes in membrane tension by undergoing a major structural change from its 'down' state to...

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Bibliographic Details
Main Authors: Nematian-Ardestani, E, Jarerattanachat, V, Aryal, P, Sansom, M, Tucker, S
Format: Journal article
Language:English
Published: Taylor and Francis 2017