Advancing artemisinin resistance monitoring using a high sensitivity ddPCR assay for Pfkelch13 mutation detection in Asia

The spread of Pfkelch13 mutations in Southeast Asia threatens the effectiveness of artemisinin-based combination therapies (ACTs) for malaria. Previous studies revealed a high prevalence of key mutations, including C580Y, P574L, and R561H, emphasizing the need for the surveillance to combat drug res...

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Bibliographic Details
Main Authors: Srisutham, S, Saejeng, A, Khantikul, N, Sugaram, R, Sangsri, R, Dondorp, AM, Day, NPJ, Imwong, M
Format: Journal article
Language:English
Published: Nature Research 2025