The evolution of drug-resistant malaria: the role of drug elimination half-life.
This paper seeks to define and quantify the influence of drug elimination half-life on the evolution of antimalarial drug resistance. There are assumed to be three general classes of susceptibility of the malaria parasite Plasmodium falciparum to a drug: Res0, the original, susceptible wildtype; Res...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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