Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration.
Midbrain dopamine neurons, which can be regulated by neuropeptides and hormones, play a fundamental role in controlling cognitive processes, reward mechanisms, and motor functions. The hormonal actions of insulin-like growth factor 1 (IGF-1) produced by the liver have been well described, but the ro...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
National Academy of Sciences
2019
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