Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration.

Midbrain dopamine neurons, which can be regulated by neuropeptides and hormones, play a fundamental role in controlling cognitive processes, reward mechanisms, and motor functions. The hormonal actions of insulin-like growth factor 1 (IGF-1) produced by the liver have been well described, but the ro...

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Bibliographic Details
Main Authors: Pristerà, A, Blomeley, C, Lopes, E, Threlfell, S, Merlini, E, Burdakov, D, Cragg, S, Guillemot, F, Ang, S
Format: Journal article
Language:English
Published: National Academy of Sciences 2019

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