Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration.
Midbrain dopamine neurons, which can be regulated by neuropeptides and hormones, play a fundamental role in controlling cognitive processes, reward mechanisms, and motor functions. The hormonal actions of insulin-like growth factor 1 (IGF-1) produced by the liver have been well described, but the ro...
Main Authors: | Pristerà, A, Blomeley, C, Lopes, E, Threlfell, S, Merlini, E, Burdakov, D, Cragg, S, Guillemot, F, Ang, S |
---|---|
Format: | Journal article |
Language: | English |
Published: |
National Academy of Sciences
2019
|
Similar Items
-
A choreography of nicotinic receptors directs the dopamine neuron routine.
by: Ungless, M, et al.
Published: (2006) -
Morphine disinhibits glutamatergic input to VTA dopamine neurons and promotes dopamine neuron excitation
by: Ming Chen, et al.
Published: (2015-07-01) -
Dopamine signaling in dorsal versus ventral striatum: the dynamic role of cholinergic interneurons.
by: Threlfell, S, et al.
Published: (2011) -
Dopamine signaling in dorsal versus ventral striatum: The dynamic role of cholinergic interneurons
by: Threlfell, S, et al.
Published: (2011) -
Impairment of macroautophagy in dopamine neurons has opposing effects on parkinsonian pathology and behaviour
by: Hunn, B, et al.
Published: (2019)