IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer
<p>Background: Activated type 1 IGF receptors (IGF-1Rs) undergo internalisation and nuclear translocation, promoting cell survival. We reported that IGF-1R inhibition delays DNA damage repair, sensitising prostate cancer cells to ionising radiation. Here, we tested the clinical relevance of th...
| Автори: | , , , , , , , , , , , , , |
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| Формат: | Journal article |
| Опубліковано: |
Cancer Research UK
2017
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