A Nonsense Mutation in TLR5 Is Associated with Survival and Reduced IL-10 and TNF-α Levels in Human Melioidosis

Background<br/> Melioidosis, caused by the flagellated bacterium Burkholderia pseudomallei, is a life-threatening and increasingly recognized emerging disease. Toll-like receptor (TLR) 5 is a germline-encoded pattern recognition receptor to bacterial flagellin. We evaluated the association of...

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Bibliographic Details
Main Authors: Chaichana, P, Chantratita, N, Brod, F, Koosakulnirand, S, Jenjaroen, K, Chumseng, S, Sumonwiriya, M, Burtnick, M, Brett, P, Teparrukkul, P, Limmathurotsakul, D, Day, N, Dunachie, S, West, T
Format: Journal article
Published: Public Library of Science 2017