Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness

The emergence of mutant K13-mediated artemisinin (ART) resistance in Plasmodium falciparum malaria parasites has led to widespread treatment failures across Southeast Asia. In Africa, K13-propeller genotyping confirms the emergence of the R561H mutation in Rwanda and highlights the continuing domina...

書誌詳細
主要な著者:	Stokes, BH, Dhingra, SK, Rubiano, K, Mok, S, Straimer, J, Gnädig, NF, Deni, I, Schindler, KA, Bath, JR, Ward, KE, Striepen, J, Yeo, T, Ross, LS, Legrand, E, Ariey, F, Cunningham, CH, Souleymane, IM, Gansané, A, Nzoumbou-Boko, R, Ndayikunda, C, Kabanywanyi, AM, Uwimana, A, Smith, SJ, Kolley, O, Ndounga, M, Warsame, M, Leang, R, Nosten, F, Anderson, TJ, Rosenthal, PJ, Ménard, D, Fidock, DA
フォーマット:	Journal article
言語:	English
出版事項:	eLife Sciences Publications 2021

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