Exploring ligand recognition and ion flow in comparative models of the human GABA type A receptor.

We present two comparative models of the GABA(A) receptor. Model 1 is based on the 4-A resolution structure of the nicotinic acetylcholine receptor from Torpedo marmorata and represents the unliganded receptor. Two agonists, GABA and muscimol, two benzodiazepines, flunitrazepam and alprazolam, toget...

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Bibliographic Details
Main Authors: Mokrab, Y, Bavro, V, Mizuguchi, K, Todorov, N, Martin, I, Dunn, S, Chan, S, Chau, P
Format: Journal article
Language:English
Published: 2007