Exploring ligand recognition and ion flow in comparative models of the human GABA type A receptor.
We present two comparative models of the GABA(A) receptor. Model 1 is based on the 4-A resolution structure of the nicotinic acetylcholine receptor from Torpedo marmorata and represents the unliganded receptor. Two agonists, GABA and muscimol, two benzodiazepines, flunitrazepam and alprazolam, toget...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2007
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