Binding strength and dynamics of invariant natural killer cell T cell receptor/CD1d-glycosphingolipid interaction on living cells by single molecule force spectroscopy.

Invariant natural killer T (iNKT) cells are a population of T lymphocytes that play an important role in regulating immunity to infection and tumors by recognizing endogenous and exogenous CD1d-bound lipid molecules. Using soluble iNKT T cell receptor (TCR) molecules, we applied single molecule forc...

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Bibliographic Details
Main Authors: Bozna, B, Polzella, P, Rankl, C, Zhu, R, Salio, M, Shepherd, D, Duman, M, Cerundolo, V, Hinterdorfer, P
Format: Journal article
Language:English
Published: 2011