Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

We have explored whether gamma-aminobutyric acid (GABA) is released by regulated exocytosis of GABA-containing synaptic-like microvesicles (SLMVs) in insulin-releasing rat pancreatic beta-cells. To this end, beta-cells were engineered to express GABA(A)-receptor Cl(-)-channels at high density using...

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Váldodahkkit: Braun, M, Wendt, A, Birnir, B, Broman, J, Eliasson, L, Galvanovskis, J, Gromada, J, Mulder, H, Rorsman, P
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2004