A novel domain suggests a ciliary function for ASPM, a brain size determining gene.

The N-terminal domain of abnormal spindle-like microcephaly-associated protein (ASPM) is identified as a member of a novel family of ASH (ASPM, SPD-2, Hydin) domains. These domains are present in proteins associated with cilia, flagella, the centrosome and the Golgi complex, and in Hydin and OCRL wh...

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Bibliografische gegevens
Hoofdauteur: Ponting, C
Formaat: Journal article
Taal:English
Gepubliceerd in: 2006