A novel domain suggests a ciliary function for ASPM, a brain size determining gene.
The N-terminal domain of abnormal spindle-like microcephaly-associated protein (ASPM) is identified as a member of a novel family of ASH (ASPM, SPD-2, Hydin) domains. These domains are present in proteins associated with cilia, flagella, the centrosome and the Golgi complex, and in Hydin and OCRL wh...
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| Aineistotyyppi: | Journal article |
| Kieli: | English |
| Julkaistu: |
2006
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