Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores.

INTRODUCTION: Osteoarthritis trials usually report average changes in visual analogue scale (VAS) pain, and examine the difference between treatment and placebo. We investigated whether dichotomous responder analysis provides a more informative interpretation of drug efficacy. METHODS: Merck suppli...

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Bibliographic Details
Main Authors: Moore, R, Moore, O, Derry, S, McQuay, H
Format: Journal article
Language:English
Published: 2008