VIRAL FITNESS COST AND T CELL CROSS-RECOGNITION LIMIT VIRAL ESCAPE WITHIN A PROTECTIVE HLA-B27 RESTRICTED HEPATITIS C VIRUS SPECIFIC CD8+T CELL EPITOPE

Geahča maid

• Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.
  Dahkki: Dazert, E, et al.
  Almmustuhtton: (2009)
• Dominant influence of an HLA-B27 restricted virus-specific CD8+T cell response in viral clearance and viral adaptation in hepatitis C virus infection
  Dahkki: Neumann-Haefelin, C, et al.
  Almmustuhtton: (2005)
• Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution.
  Dahkki: Neumann-Haefelin, C, et al.
  Almmustuhtton: (2006)
• RAPID AND EFFICIENT ANTIGEN PROCESSING AND PRESENTATION OF A PROTECTIVE AND IMMUNODOMINANT HLA-B*27-RESTRICTED HEPATITIS C VIRUS-SPECIFIC CD8+T CELL EPITOPE
  Dahkki: Schmidt, J, et al.
  Almmustuhtton: (2012)
• Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.
  Dahkki: Schmidt, J, et al.
  Almmustuhtton: (2012)