Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing

Two bottlenecks impeding the genetic analysis of complex traits in rodents are access to mapping populations able to deliver gene-level mapping resolution, and the need for population specific genotyping arrays and haplotype reference panels. Here we combine low coverage sequencing (0.15X...

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Main Authors:	Nicod, J, Davies, R, Cai, N, Hassett, C, Goodstadt, L, Cosgrove, C, Yee, B, Lionikaite, V, McIntyre, R, Remme, C, Lodder, E, Gregory, J, Hough, T, Joynson, R, Phelps, H, Nell, B, Rowe, C, Wood, J, Walling, A, Bopp, N, Bhomra, A, Hernandez-Pliego, P, Callebert, J, Aspden, R, Talbot, N, Robbins, P, Harrison, M, Fray, M, Launay, J, Pinto, Y, Blizard, D, Bezzina, C, Adams, D, Franken, P, Weaver, T, Wells, S, Brown, S, Potter, P, Klenerman, P, Lionikas, A, Mott, R, Flint, J
Format:	Journal article
Language:	English
Published:	Nature Publishing Group 2016

Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing

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