A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting.
The triplet-based genetic code requires that translating ribosomes maintain the reading frame of a messenger RNA faithfully to ensure correct protein synthesis. However, in programmed -1 ribosomal frameshifting, a specific subversion of frame maintenance takes place, wherein the ribosome is forced t...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Jezik: | English |
| Izdano: |
2006
|