Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable.

BACKGROUND: The developmental overnutrition hypothesis suggests that greater maternal obesity during pregnancy results in increased offspring adiposity in later life. If true, this would result in the obesity epidemic progressing across generations irrespective of environmental or genetic changes. I...

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Bibliographic Details
Main Authors: Lawlor, D, Timpson, N, Harbord, R, Leary, S, Ness, A, McCarthy, M, Frayling, T, Hattersley, A, Smith, G
Format: Journal article
Language:English
Published: 2008