11Beta-hydroxysteroid dehydrogenase type 1 in human disease: a novel therapeutic target.
Patients with cortisol excess, Cushing's syndrome, develop a classical phenotype characterized by central obesity, hypertension, and increased cardiovascular mortality. Whilst this observation points to the importance of glucocorticoids, circulating cortisol excess is rare and does not explain...
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| Format: | Journal article |
| Langue: | English |
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2005
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