Mass spectrometry reveals the missing links in the assembly pathway of the bacterial 20 S proteasome.

The 20 S proteasome is an essential proteolytic particle, responsible for degrading short-lived and abnormal intracellular proteins. The 700-kDa assembly is comprised of 14 alpha-type and 14 beta-type subunits, which form a cylindrical architecture composed of four stacked heptameric rings (alpha7be...

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Bibliografische gegevens
Hoofdauteurs: Sharon, M, Witt, S, Glasmacher, E, Baumeister, W, Robinson, C
Formaat: Journal article
Taal:English
Gepubliceerd in: 2007