Genome-wide association study identifies 74 loci associated with educational attainment

Educational attainment is strongly influenced by social and other environmental factors, but genetic factors are estimated to account for at least 20% of the variation across individuals1. Here we report the results of a genome-wide association study (GWAS) for educational attainment that extends...

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Main Authors: Okbay, A, Beauchamp, J, Fontana, M, Lee, J, Pers, T, Rietveld, C, Turley, P, Chen, G, Emilsson, V, Meddens, S, Oskarsson, S, Pickrell, J, Thom, K, Timshel, P, de Vlaming, R, Abdellaoui, A, Ahluwalia, T, Bacelis, J, Baumbach, C, Bjornsdottir, G, Brandsma, J, Concas, M, Derringer, J, Furlotte, N, Galesloot, T, Girotto, G, Gupta, R, Hall, L, Harris, S, Hofer, E, Horikoshi, M, Huffman, J, Kaasik, K, Kalafati, I, Karlsson, R, Kong, A, Lahti, J, van der Lee, S, de Leeuw, C, Lind, P, Lindgren, K, Liu, T, Mangino, M, Marten, J, Mihailov, E, Miller, M, van der Most, P, Oldmeadow, C, Payton, A, Pervjakova, N, Peyrot, W, Qian, Y, Raitakari, O, Rueedi, R, Salvi, E, Schmidt, B, Schraut, K, Shi, J, Smith, A, Poot, R, St Pourcain, B, Teumer, A, Thorleifsson, G, Verweij, N, Vuckovic, D, Wellmann, J, Westra, H, Yang, J, Zhao, W, Zhihong, Z, Alizadeh, B, Amin, N, Bakshi, A, Baumeister, S, Biino, G, Bønnelykke, K, Boyle, P, Campbell, H, Cappuccio, F, Davies, G, De Neve, J, Deloukas, P, Demuth, I, Ding, J, Eibich, P, Eisele, L, Eklund, N, Evans, D, Faul, J, Feitosa, M, Forstner, A, Gandin, I, Gunnarsson, B, Halldórsson, B, Harris, T, Heath, A, Hocking, L, Holliday, E, Homuth, G, Horan, M, Hottenga, J, de Jager, P, Joshi, P, Jugessur, A, Kaakinen, M, Kähönen, M, Kanoni, S, Keltigangas-Järvinen, L, Kiemeney, L, Kolcic, I, Koskinen, S, Kraja, A, Kroh, M, Kutalik, Z, Latvala, A, Launer, L, Lebreton, M, Levinson, D, Lichtenstein, P, Lichtner, P, Liewald, D, LifeLines Cohort Study, Loukola, A, Madden, P, Mägi, R, Mäki-Opas, T, Marioni, R, Marques-Vidal, P, Meddens, G, McMahon, G, Meisinger, C, Meitinger, T, Milaneschi, Y, Milani, L, Montgomery, G, Myhre, R, Nelson, C, Nyholt, D, Ollier, W, Palotie, A, Paternoster, L, Pedersen, N, Petrovic, K, Porteous, D, Räikkönen, K, Ring, S, Robino, A, Rostapshova, O, Rudan, I, Rustichini, A, Salomaa, V, Sanders, A, Sarin, A, Schmidt, H, Scott, R, Smith, B, Smith, J, Staessen, J, Steinhagen-Thiessen, E, Strauch, K, Terracciano, A, Tobin, M, Ulivi, S, Vaccargiu, S, Quaye, L, van Rooij, F, Venturini, C, Vinkhuyzen, A, Völker, U, Völzke, H, Vonk, J, Vozzi, D, Waage, J, Ware, E, Willemsen, G, Attia, J, Bennett, D, Berger, K, Bertram, L, Bisgaard, H, Boomsma, D, Borecki, I, Bultmann, U, Chabris, C, Cucca, F, Cusi, D, Deary, I, Dedoussis, G, van Duijn, C, Eriksson, J, Franke, B, Franke, L, Gasparini, P, Gejman, P, Gieger, C, Grabe, H, Gratten, J, Groenen, P, Gudnason, V, van der Harst, P, Hayward, C, Hinds, D, Hoffmann, W, Hyppönen, E, Iacono, W, Jacobsson, B, Järvelin, M, Jöckel, K, Kaprio, J, Kardia, S, Lehtimäki, T, Lehrer, S, Magnusson, P, Martin, N, McGue, M, Metspalu, A, Pendleton, N, Penninx, B, Perola, M, Pirastu, N, Pirastu, M, Polasek, O, Posthuma, D, Power, C, Province, M, Samani, N, Schlessinger, D, Schmidt, R, Sørensen, T, Spector, T, Stefansson, K, Thorsteinsdottir, U, Thurik, A, Timpson, N, Tiemeier, H, Tung, J, Uitterlinden, A, Vitart, V, Vollenweider, P, Weir, D, Wilson, J, Wright, A, Conley, D, Krueger, R, Smith, G, Hofman, A, Laibson, D, Medland, S, Meyer, M, Johannesson, M, Visscher, P, Esko, T, Koellinger, P, Cesarini, D, Benjamin, D
Format: Journal article
Published: Nature Publishing Group 2016