Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina
There is much debate on the adeno-associated virus (AAV) serotype that best targets specific retinal cell types and the route of surgical delivery — intravitreal or subretinal. This study compared three of the most efficacious AAV vectors known to date in a mouse model of retinal degeneration (rd1 m...
| Main Authors: | , , , , , , , , |
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| 格式: | Journal article |
| 出版: |
Nature Publishing Group
2017
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