Role of Capsid anchor in the morphogenesis of Zika virus

The flavivirus capsid protein (C) is separated from the downstream pre-membrane (PrM) protein by a hydrophobic sequence named capsid anchor (Ca). During polyprotein processing, Ca is sequentially cleaved by the viral NS2B/NS3 protease on the cytosolic side and by signal peptidase on the luminal side...

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Bibliographic Details
Main Authors: Rana, J, Slon Campos, J, Leccese, G, Francolini, M, Bestagno, M, Poggianella, M, Burrone, O
Format: Journal article
Language:English
Published: American Society for Microbiology 2018