Multisite phosphorylation in T cell receptor proximal signalling

<p>T cell receptor proximal signalling represents a specific instance of a multisite phosphorylation system. Receptor phosphorylation is regulated by the opposing actions of the kinase LCK, and phosphatases such as CD45 and CD148. Particular phosphoforms recruit the kinase ZAP-70, which once b...

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Detalhes bibliográficos
Autor principal: Mukhopadhyay, H
Outros Autores: Dushek, O
Formato: Tese
Publicado em: 2015