CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression.
The CD40-CD40 ligand (CD40L) interaction is a key event in the initiation of an adaptive immune response, and as such the therapeutic value of CD40L blockade has been studied in many experimental models of tissue transplantation and autoimmune disease. In rodents, transplantation of allogeneic tissu...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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