Studies on the inhibition of human hypoxia inducible factor (HIF) hydroxylases

<p>Hypoxia inducible factor (HIF) is an α/β-heterodimeric transcription factor that regulates cellular responses to hypoxia in metazoans. The activity and stability of the HIF-α subunits are regulated by prolyl and asparaginyl hydroxylation. Human HIF-1α prolyl hydroxylation occurs at Pro402 a...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur: Yeoh, KK
Awduron Eraill: Schofiled, CJ
Fformat: Traethawd Ymchwil
Iaith:English
Cyhoeddwyd: 2012
Pynciau: