A combined 3D-SIM/SMLM approach allows centriole proteins to be localised with a precision of ~4-5nm

Centrioles are small barrel-shaped structures that form centrosomes and cilia [1]. Centrioles assemble around a central cartwheel comprising the Sas-6 and Ana2/STIL proteins. The amino termini of nine Sas-6 dimers form a central hub of ∼12 nm radius from which nine dimer spokes radiate, placing the...

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Bibliographic Details
Main Authors: Gartenmann, L, Wainman, A, Qurashi, M, Kaufmann, R, Schubert, S, Raff, J, Dobbie, I
Format: Journal article
Published: Cell Press 2017