The structural basis of ZMPSTE24-dependent laminopathies.

The structural basis of ZMPSTE24-dependent laminopathies.

عرض إصدارات أخرى (1)

Mutations in the nuclear membrane zinc metalloprotease ZMPSTE24 lead to diseases of lamin processing (laminopathies), such as the premature aging disease progeria and metabolic disorders. ZMPSTE24 processes prelamin A, a component of the nuclear lamina intermediate filaments, by cleaving it at two s...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Quigley, A, Dong, Y, Pike, A, Dong, L, Shrestha, L, Berridge, G, Stansfeld, P, Sansom, MS, Edwards, A, Bountra, C, von Delft, F, Bullock, A, Burgess-Brown, N, Carpenter, E
التنسيق: Journal article
اللغة:English
منشور في: 2013

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