K(+) versus Na(+) ions in a K channel selectivity filter: a simulation study.
Molecular dynamics simulations of a bacterial potassium channel (KcsA) embedded in a phospholipid bilayer reveal significant differences in interactions of the selectivity filter with K(+) compared with Na(+) ions. K(+) ions and water molecules within the filter undergo concerted single-file motion...
Autori principali: | Shrivastava, I, Tieleman, D, Biggin, P, Sansom, MS |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2002
|
Documenti analoghi
Documenti analoghi
-
Simulation approaches to ion channel structure-function relationships.
di: Tieleman, D, et al.
Pubblicazione: (2001) -
Understanding pH-dependent selectivity of alamethicin K18 channels by computer simulation.
di: Tieleman, D, et al.
Pubblicazione: (2003) -
The selectivity of K+ ion channels: testing the hypotheses.
di: Fowler, P, et al.
Pubblicazione: (2008) -
Potassium and sodium ions in a potassium channel studied by molecular dynamics simulations.
di: Biggin, P, et al.
Pubblicazione: (2001) -
Gating at the selectivity filter of ion channels that conduct Na+ and K+ ions.
di: Furini, S, et al.
Pubblicazione: (2011)