Role of the proteasome and non proteasomal proteases in the generation of CTL epitopes.
We have previously shown that cells lacking the MHC encoded proteasome subunits LMP2 and LMP7 have a severe defect in the generation of the HLA-A2 restricted influenza Matrix epitope 58-66. We have now extended this observation to other viral epitopes and demonstrated that the antigen presentation b...
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
1998
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