Role of the proteasome and non proteasomal proteases in the generation of CTL epitopes.

Role of the proteasome and non proteasomal proteases in the generation of CTL epitopes.

We have previously shown that cells lacking the MHC encoded proteasome subunits LMP2 and LMP7 have a severe defect in the generation of the HLA-A2 restricted influenza Matrix epitope 58-66. We have now extended this observation to other viral epitopes and demonstrated that the antigen presentation b...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Cerundolo, V, Booth, B, Gileadi, U, Sewell, A, Phillips, R, Trowsdale, J, Teisserenc, H
פורמט:	Journal article
שפה:	English
יצא לאור:	1998

פריטים דומים

Generation of an immunodominant CTL epitope is affected by proteasome subunit composition and stability of the antigenic protein.
מאת: Gileadi, U, et al.
יצא לאור: (1999)

Effects of retroviral protease inhibitors on proteasome function and processing of HIV-derived MHC class I-restricted cytotoxic T lymphocyte epitopes.
מאת: Kelleher, A, et al.
יצא לאור: (2001)

CD8+ T cell epitope-flanking mutations disrupt proteasomal processing of HIV-1 Nef.
מאת: Milicic, A, et al.
יצא לאור: (2005)

Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes
מאת: Ebstein, F, et al.
יצא לאור: (2016)

An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses.
מאת: André, P, et al.
יצא לאור: (1998)

IFN-gamma exposes a cryptic cytotoxic T lymphocyte epitope in HIV-1 reverse transcriptase.
מאת: Sewell, A, et al.
יצא לאור: (1999)

The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells.
מאת: Cerundolo, V, et al.
יצא לאור: (1997)

Peptide splicing by the proteasome.
מאת: Vigneron, N, et al.
יצא לאור: (2017)

Substrate recognition by the proteasome
מאת: Boehringer, J
יצא לאור: (2011)

Production of spliced peptides by the proteasome
מאת: Vigneron, N, et al.
יצא לאור: (2018)

The ubiquitin-proteasome pathway in cancer.
מאת: Spataro, V, et al.
יצא לאור: (1998)

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome
מאת: Tsvetkov, Peter, et al.
יצא לאור: (2015)

Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3.
מאת: Valmori, D, et al.
יצא לאור: (1999)

Role of the immuno-proteasome in CD8 responses to MCMV
מאת: Hutchinson, SL
יצא לאור: (2009)

Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections
מאת: Misas-Villamil, J, et al.
יצא לאור: (2017)

Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.
מאת: Edwards, C, et al.
יצא לאור: (2009)

Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
מאת: Ernst, Robert, et al.
יצא לאור: (2011)

Proteasome inhibitors as anti-cancer agents.
מאת: Murray, R, et al.
יצא לאור: (2000)

Functional differences between proteasome subtypes
מאת: Abi Habib, J, et al.
יצא לאור: (2022)

Tight metabolic coupling of the proteasome with downstream oligopeptidases.
מאת: Wang, E, et al.
יצא לאור: (1999)

Elucidation of the signatures of proteasome-catalysed peptide splicing
מאת: Paes, W, et al.
יצא לאור: (2020)

The ubiquitin-proteasome system regulates chloroplast biogenesis.
מאת: Huang, W, et al.
יצא לאור: (2013)

Cks1 activates transcription by binding to the ubiquitylated proteasome.
מאת: Holic, R, et al.
יצא לאור: (2010)

Human T-cell leukemia virus type 1 Tax protein binds to assembled nuclear proteasomes and enhances their proteolytic activity.
מאת: Hemelaar, J, et al.
יצא לאור: (2001)

LMP2 expression and proteasome activity in NOD mice.
מאת: Kessler, B, et al.
יצא לאור: (2000)

LMP2 expression and proteasome activity in NOD mice
מאת: Kessler, B, et al.
יצא לאור: (2000)

Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities.
מאת: Gu, C, et al.
יצא לאור: (2010)

Architecture and assembly of the archaeal Cdc48*20S proteasome
מאת: Barthelme, Dominik, et al.
יצא לאור: (2014)

Regulation of nicotinic receptor expression by the ubiquitin-proteasome system.
מאת: Christianson, J, et al.
יצא לאור: (2004)

The interaction between HTLV-1 Tax protein and the proteasome
מאת: Hemelaar, J, et al.
יצא לאור: (2001)

Requirement of the proteasome for the trimming of signal peptide-derived epitopes presented by the nonclassical major histocompatibility complex class I molecule HLA-E.
מאת: Bland, F, et al.
יצא לאור: (2003)

Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins
מאת: Abi Habib, J, et al.
יצא לאור: (2020)

Proteasome activity profiling uncovers alteration of catalytic β2 and β5 subunits of the stress-induced proteasome during salinity stress in tomato roots
מאת: Kovács, J, et al.
יצא לאור: (2017)

Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity.
מאת: Wang, E, et al.
יצא לאור: (2000)

Learning from the proteasome: how to fine-tune cancer immunotherapy
מאת: Vigneron, N, et al.
יצא לאור: (2017)

Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib.
מאת: Berkers, C, et al.
יצא לאור: (2005)

Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer
מאת: Cron, Kyle R., et al.
יצא לאור: (2013)

Antigen processing defects in cervical carcinomas limit the presentation of a CTL epitope from human papillomavirus 16 E6.
מאת: Evans, M, et al.
יצא לאור: (2001)

7.340 Ubiquitination: The Proteasome and Human Disease, Fall 2004
מאת: Rubio, Marta
יצא לאור: (2023)

Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium Tuberculosis Proteasome
מאת: Totaro, Kyle A., et al.
יצא לאור: (2018)