Role of the proteasome and non proteasomal proteases in the generation of CTL epitopes.

Role of the proteasome and non proteasomal proteases in the generation of CTL epitopes.

We have previously shown that cells lacking the MHC encoded proteasome subunits LMP2 and LMP7 have a severe defect in the generation of the HLA-A2 restricted influenza Matrix epitope 58-66. We have now extended this observation to other viral epitopes and demonstrated that the antigen presentation b...

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Detalhes bibliográficos
Principais autores:	Cerundolo, V, Booth, B, Gileadi, U, Sewell, A, Phillips, R, Trowsdale, J, Teisserenc, H
Formato:	Journal article
Idioma:	English
Publicado em:	1998

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