Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence

Immunosenescence is the functional deterioration of the immune system during natural aging. Despite increased susceptibility to bacterial infections in older adults, age-associated changes to neutrophil responses are only partially understood, and neutrophil migration has not been characterized in d...

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Bibliographic Details
Main Authors: Sapey, E, Greenwood, H, Walton, G, Mann, E, Love, A, Aaronson, N, Insall, RH, Stockley, RA, Lord, JM
Format: Journal article
Language:English
Published: American Society of Hematology 2014