Chronic hepatitis C viral infection subverts vaccine-induced T-cell immunity in humans

Chronic hepatitis C viral infection subverts vaccine-induced T-cell immunity in humans

Adenoviral vectors encoding hepatitis C virus (HCV) nonstructural (NS) proteins induce multispecific, high-magnitude, durable CD4+ and CD8+ T-cell responses in healthy volunteers. We assessed the capacity of these vaccines to induce functional HCV-specific immune responses and determine T-cell cross...

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書誌詳細
主要な著者: Kelly, C, Swadling, L, Capone, S, Brown, A, Richardson, R, Halliday, J, von Delft, A, Oo, Y, Mutimer, D, Kurioka, A, Hartnell, F, Collier, J, Ammendola, V, Sorbo, M, Grazioli, F, Esposito, M, Marco, S, Siani, L, Traboni, C, Hill, A, Colloca, S, Nicosia, A, Cortese, R, Folgori, A, Klenerman, P, Barnes, E
フォーマット: Journal article
言語:English
出版事項: Wiley 2016

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