The biochemistry and immunology of non-canonical forms of HLA-B27
HLA-B27 (B27) is strongly associated with the spondyloarthritides. B27 is expressed at the cell surface of antigen presenting cells (APC) both as canonical β2m-associated and non-canonical β2m-free heavy chain (FHC) forms which include B27 dimers (termed B272). B27 FHC forms arise in an endosomal co...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2014
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