The biochemistry and immunology of non-canonical forms of HLA-B27

HLA-B27 (B27) is strongly associated with the spondyloarthritides. B27 is expressed at the cell surface of antigen presenting cells (APC) both as canonical β2m-associated and non-canonical β2m-free heavy chain (FHC) forms which include B27 dimers (termed B272). B27 FHC forms arise in an endosomal co...

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Bibliographic Details
Main Authors: Shaw, J, Hatano, H, Kollnberger, S
Format: Journal article
Language:English
Published: 2014