A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

Alzheimer's disease (AD) involves progressive accumulation of amyloid β-peptide (Aβ) and neurofibrillary pathologies, and glucose hypometabolism in brain regions critical for memory. The 3xTgAD mouse model was used to test the hypothesis that a ketone ester-based diet can ameliorate AD pathogen...

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Bibliographic Details
Main Authors: Kashiwaya, Y, Bergman, C, Lee, J, Wan, R, King, M, Mughal, MR, Okun, E, Clarke, K, Mattson, M, Veech, R
Format: Journal article
Published: 2013