Targeting OXPHOS and the electron transport chain in cancer; molecular and therapeutic implications

Oxidative phosphorylation (OXPHOS) takes place in mitochondria and is the process whereby cells use carbon fuels and oxygen to generate ATP. Formerly OXPHOS was thought to be reduced in tumours and that glycolysis was the critical pathway for generation of ATP but it is now clear that OXPHOS, at lea...

詳細記述

書誌詳細
主要な著者: Greene, J, Segaran, A, Lord, S
フォーマット: Journal article
言語:English
出版事項: Elsevier 2022