T cell regulation in adult transplantation tolerance.

An encounter of the mature immune system with Ag usually leads to an immune response. If Ag is administered with CD4- and CD8-specific mAbs, the outcome of the response can be tolerance. This form of tolerance is peripheral, Ag specific, and maintained lifelong, and is associated with the suppressio...

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Bibliographic Details
Main Authors: Davies, J, Martin, G, Phillips, J, Marshall, SE, Cobbold, S, Waldmann, H
Format: Journal article
Language:English
Published: 1996