Evolutionary analyses of base-pairing interactions in DNA and RNA secondary structures
Pairs of nucleotides within functional nucleic acid secondary structures often display evidence of coevolution that is consistent with the maintenance of base-pairing. Here we introduce a sequence evolution model, MESSI, that infers coevolution associated with base-paired sites in DNA or RNA sequenc...
| Main Authors: | , , , , |
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| Format: | Working paper |
| Published: |
2019
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