Human immunodeficiency virus infection impairs Th1 and Th17 Mycobacterium tuberculosis–specific T-cell responses

Human immunodeficiency virus (HIV)-infected individuals have a higher risk of developing active tuberculosis (TB) than HIV-uninfected individuals, but the mechanisms underpinning this are unclear. We hypothesized that depletion of specific components of Mycobacterium tuberculosis (Mtb)-specific CD4+...

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Bibliographic Details
Main Authors: Murray, L, Satti, I, Meyerowitz, J, Jones, M, Willberg, C, Ussher, J, Goedhals, D, Hurst, J, Phillips, R, McShane, H, Vuuren, C, Frater, J
Format: Journal article
Language:English
Published: Oxford University Press 2018