Identifying novel substrates of salt-inducible kinase 2

<p>Salt-inducible kinase 2 (SIK2) has previously been identified as a potential therapeutic target in high-grade serous ovarian cancer. Depletion of SIK2 sensitises ovarian cancers to paclitaxel treatment both <em>in vitro</em> and in xenograft models. In patients, increased tumour...

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Bibliographic Details
Main Author: Mannion, D
Other Authors: Ahmed, A
Format: Thesis
Language:English
Published: 2016
Subjects: