Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections.

IL-2 is a cytokine with multiple and even divergent functions; it has been described as a key cytokine for in vitro T cell proliferation but is also essential for down-regulating T cell responses by inducing activation-induced cell death as well as regulatory T cells. The in vivo analysis of IL-2 fu...

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Bibliographic Details
Main Authors: Bachmann, M, Wolint, P, Walton, S, Schwarz, K, Oxenius, A
Format: Journal article
Language:English
Published: 2007