Improving SRM assay development: a global comparison between triple quadrupole, ion trap, and higher energy CID peptide fragmentation spectra.

In proteomics, selected reaction monitoring (SRM) is rapidly gaining importance for targeted protein quantification. The triple quadrupole mass analyzers used in SRM assays allow for levels of specificity and sensitivity hard to accomplish by more standard shotgun proteomics experiments. Often, an S...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: de Graaf, E, Altelaar, A, van Breukelen, B, Mohammed, S, Heck, A
Materialtyp: Journal article
Språk:English
Publicerad: 2011