A prospective, blinded analysis of thymidylate synthase and p53 expression as prognostic markers in the adjuvant treatment of colorectal cancer.
BACKGROUND: Despite previous studies, uncertainty has persisted about the role of thymidylate synthase (TS) and p53 status as markers of prognosis in colorectal cancer (CRC). PATIENTS AND METHODS: A total of 967 patients accrued to a large adjuvant trial in CRC were included in a prospectively plan...
Main Authors: | Popat, S, Chen, Z, Zhao, D, Pan, H, Hearle, N, Chandler, I, Shao, Y, Aherne, W, Houlston, R |
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Format: | Journal article |
Language: | English |
Published: |
2006
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