Altered contractile mechanics and Ca2+ handling contribute to cardiomyopathy pathogenesis
<p>Mutations in genes encoding sarcomeric proteins are the most common cause of inherited cardiomyopathies. However, cardiac disease caused by mutations in non-sarcomeric proteins exhibit remarkably similar phenotypes, suggesting that common modes of pathogenesis might exist. It is of particul...
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| Format: | Thesis |
| Language: | English |
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2015
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