Does anti-EGFR therapy improve outcome in advanced colorectal cancer? A systematic review and meta-analysis.
BACKGROUND: Randomised controlled trials (RCTs) of anti-EGFR monoclonal antibodies (MAb) in patients with advanced colorectal cancer (aCRC) have reported conflicting results. METHODS: A systematic review of RCTs comparing standard treatments±anti-EGFR MAbs was conducted. Hazard ratios (HR) for progr...
Main Authors: | Vale, C, Tierney, J, Fisher, D, Adams, R, Kaplan, R, Maughan, T, Parmar, M, Meade, A |
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Format: | Journal article |
Language: | English |
Published: |
2012
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