Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: replication using a population case control and family-based study.

Early case control studies found association of the DRB1 allele, DR3, with Graves' disease (GD). Recent reports, claim the DQA1 allele, DQA1*0501, to be the primary susceptibility determinant within the human leukocyte antigen (HLA) class II region. We typed 228 GD patients, 364 controls, and 9...

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Bibliographic Details
Main Authors: Heward, J, Allahabadia, A, Daykin, J, Carr-Smith, J, Daly, A, Armitage, M, Dodson, P, Sheppard, M, Barnett, A, Franklyn, J, Gough, S
Format: Journal article
Language:English
Published: 1998