Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sezary syndrome from other cutaneous T-cell lymphomas.

Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sezary syndrome from other cutaneous T-cell lymphomas.

Cutaneous T-cell lymphomas (CTCL) are mainly comprised of two variants: mycosis fungoides (MF) with CD4(+) tumor cells confined to the skin and the leukemic Sézary syndrome with tumor cell spread to the blood. In this study, we investigated cutaneous expression of the regulatory T-cell (T(reg)) mark...

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Bibliographic Details
Main Authors: Klemke, C, Fritzsching, B, Franz, B, Kleinmann, E, Oberle, N, Poenitz, N, Sykora, J, Banham, A, Roncador, G, Kuhn, A, Goerdt, S, Krammer, P, Suri-Payer, E
Format: Journal article
Language:English
Published: 2006

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